Catalytic Stereoselective Conjugate Addition of Oxindole to Electron-Deficient Alkynes
A Z/E-selective and enantioselective conjugate addition of oxindoles to butyl but-2-ynedioate derivatives has been developed, providing a facile access to enantioenriched multifunctional olefins, which can be further converted into 3,3a- dihydro-2H-pyrrolo[3,4-c]quinoline-1,4(5H,9bH)-dione derivatives via conventional operations.
