个 人 简 介 |  徐清,男,汉族,1977年11月出生,浙江永康人,中共党员、教授、博士、博导,中国化学会会员。1999年6月毕业于浙江大学化学系,获理学学士学位;同年保送浙江大学硕博连读研究生,2004年6月获理学博士学位(导师:黄宪院士);2004年10月赴日本产业技术综合研究所(National Institute of Advanced Industrial Science and Technology, AIST),作为特别研究员从事手性有机膦化合物合成与应用研究(合作导师:Li-Biao Han教授);2009年2月进入温州大学杏吧视频
从事教学科研工作;2012年12月破格晋升教授职称;2015年3月--9月美国威斯康辛大学麦迪逊分校(University of Wisconsin-Madison)访问学者(合作教授:Shannon Stahl)。2014年获浙江省杰出青年基金,入选2016年江苏省企业创新“双创人才”、浙江省***人才工程第二层次、浙江省高校优秀青年教师、温州市***人才工程第一层次、“温州市特聘专家”、第十三届“温州市十大杰出青年”、2015年淮安市“淮上英才计划” 创新创业领军人才,温州市青年联合会第八届委员会委员、温州大学青年博士联谊会副会长、温州大学首届“学生科技创新十佳指导教师”。研究方向为绿色化学和绿色合成研究、过渡金属催化反应研究、高选择元素有机化合物合成应用研究、不对称催化与合成研究,以及相关新反应机理研究。在醇活化应用领域发展了多种醇活化新策略、在世界上首次提出“接力”方法学及其机理,提升了醇活化理论、促进拓展了绿色的醇类化合物在医药农药等中间体中的合成应用,获国内外同行专家广泛认可。至今已在J. Am. Chem. Soc.、Angewan. Chem.、Green Chem.、ChemSusChem、Org. Lett.、Chem. Commun.、J. Catal.、Adv. Synth. Catal.、Chem. Eur. J.、Top. Curr. Chem、J. Org. Chem.、Catal. Sci. Technol.、Org. Biomol. Chem.、Mini-Rev. Med. Chem.、RSC Adv.、Tetrahedron、Catal. Lett.、Synlett.、Tetrahedron Lett.、J. Organometallic Chem.等国际SCI学术期刊发表近百篇学术论文,申请三十多项国内外发明专利、已获授权二十多项;. (SCI新一区,IF 7.411)  (2) Haicheng Liu, Jianping Liu,* Xiaokai Cheng, Xiaojuan Jia, Lei Yu, Qing Xu,* DMSO-triggered complete oxygen transfer leading to accelerated aqueous hydrolysis of organohalides under mild conditions, ChemSusChem, 2019, . (SCI新一区,IF 7.411).   (3) Chao Chen, Xu Zhang, Hongen Cao, Fang Wang, Lei Yu* and Qing Xu*, Iron-Enabled Utilization of Air as the Terminal Oxidant Leading to Aerobic Oxidative Deoximation by Organoselenium Catalysis, Adv. Synth. Catal. 2019, 361 (3), 603-610. . (SCI二区)  (4) Xiantao Ma, Qing Xu,* Huan Li, Chneliang Su, Lei Yu, Xu Zhang, Hongen Cao and Li-Biao Han,* Alcohol-Based Michaelis-Arbuzov Reaction: an Efficient and Environmentally-Benign Way for C-P(O) Bond Formation. Green Chem. 2018, 20 (15), 3408-3413. (SCI新一区,IF 8.506). Highlighted by Green Chem. as Back Cover Paper.   (5) Bin Feng, Yang Li, Huan Li, Xu Zhang, Huamei, Xie, Hongen Cao, Lei Yu, and Qing Xu,* Specific N-Alkylation of Hydroxypyridines Achieved by a Catalyst- and Base-Free Reaction with Organohalides. J. Org. Chem. 2018, 83 (12), 6769–6775. (SCI-II)  (6) Yonghong Liu,† Daliang Tang,† Kuanhong Cao, † Lei Yu,* Jie Han* and Qing Xu* (†These authors contributed equally), Probing the support effect at the molecular level in polyanilines-supported palladium nanoparticles-catalyzed Ullmann reaction of aryl iodides. J. Catal. 2018, 360, 250-260. (SCI新一区)  (7) Dongliang Zhang,† Yaping Huang,†, Erlei Zhang,† Rong Yi,† Chao Chen,† Lei Yu,* and Qing Xu* (†These authors contributed equally), Pd/Mn Bimetallic Relay Catalysis for Aerobic Aldoxime Dehydration to Nitriles, Adv. Synth. Catal. 2018, 360 (4), 784-790. (SCI新一区,影响因子6.567).  (8) Yaqi Yang, Zihang Ye, Xu Zhang, Yipeng Zhou, Xiantao Ma, Hongen Cao, Huan Li, Lei Yu, and Qing Xu,* Efficient dehydrative alkylation of thiols with alcohols catalyzed by alkyl halides, Org. Biomol. Chem. 2017, 15 (45), 9638-9642. (SCI-II)  (9) Song Yao, Kaijing Zhou, Jiabing Wang, Hongen Cao, Lei Yu, Jianzhang Wu,* Peihong Qiu,* Qing Xu.* Synthesis of 2-Subsitituted Quinazolines by CsOH-Mediated Highlighted by X-mol:  (10) Xiantao Ma, Lei Yu, Chenliang Su,* Yaqi Yang, Huan Li, and Qing Xu*, Efficient Generation of C-S Bonds via a Byproduct-Promoted Selective Coupling of Alcohols, Organohalides, and Thiourea. Adv. Synth. Catal. 2017, 359, 1649-1655. (SCI新一区,影响因子6.567). . 

(11) Jianhui Chen,† Yang Li,† Shuangyan Li, Jianping Liu,* Fei Zheng, Zhengping Zhang, and Qing Xu*, Aldehyde/Ketone-Catalyzed Highly Selective Synthesis of 9-Monoalkylated Fluorenes by Dehydrative C-Alkylation with Primary and Secondary Alcohols, Green Chem. 2017, 19 (1), 623-628. (SCI新一区,IF 8.506)  (12) Xiang Ren, Qihang Guo, Jianhui Chen, Hujun Xie,* Qing Xu* and Zhan Lu*. Visible-Light Promoted Distereodivergent Intramolecular Oxyamidation of Alkenes. Chem. Eur. J. 2016, 22 (52), 18695-18699. (SCI-II, IF: 5.731)  (13) Xiaokai Cheng, Bo Yang, Xingen Hu, Qing Xu, and Zhan Lu,* Visible-Light-Promoted Metal-Free Aerobic Oxidation of Primary Amines to Acids and Lactones. Chem. Eur. J. 2016, 22 (49), 17566-17570. (SCI-II, IF: 5.731)  (14) Yang Li, Haonan Chen, Jianping Liu,* Xujun Wan, and Qing Xu*, Clean Synthesis of Primary to Tertiary Carboxamides by CsOH-Catalyzed Aminolysis of Nitriles in Water, Green Chem. 2016, 18 (18), 4865–4870. (SCI-II, IF 8.506) (15)  (16) Wang, Wei-Min; Liu, Li-Juan; Yao, Lan; Meng, Fan-Jie; Sun, Yong-Ming; Zhao, Chang-Qiu; Xu, Qing; Han, Li-Biao. Stereospecific Preparations of P-Stereogenic Phosphonothioates and Phosphonoselenoates. J. Org. Chem. 2016, 81 (15), 6843-6847. (SCI-II,IF: 4.721)  (17) Jianping Liu,* Chao Wang, Xiantao Ma, Xinkang Shi, Xin Wang, Huan Li, and Qing Xu.* Simple Synthesis of Benzazoles by Substrate-Promoted CuI-Catalyzed Aerobic Oxidative Cyclocondensation of o-Thio/Amino/Hydroxyanilines and Amines under Air. Catal. Lett. 2016, 146 (10), 2139-2148 (SCI-III, IF 2.294) DOI: 10.1007/s10562-016-1818-2  (18) Qing Xu,* Huamei Xie, Er-Lei Zhang, Xiantao Ma, Jianhui Chen, Xiao-Chun Yu, and Huan Li. Selective Catalytic Hoffmann N-Alkylation of Poor Nucleophilic Amines and Amides with Catalytic Amounts of Alkyl Halides. Green. Chem. 2016, 18 (14), 3940-3944. (SCI-II, IF: 8.506).  (19) Xiantao Ma, Quan Liu, Xiaojuan Jia, Chenliang Su* and Qing Xu*, Efficient Synthesis of Unsymmetrical Heteroaryl Thioethers and Chalcogenides by Alkali Hydroxide-Mediated SNAr Reactions of Heteroaryl Halides and Dichalcogenides, RSC Adv. 2016, 6 (62), 56930-56935. (IF 3.84).  (20) Xiantao Ma, Chenliang Su, Qing Xu*,  (21) Qiang Li, Tieqiao Chen, Qing Xu,* Li-Biao Han.* Rhodium- and Iridium-Catalyzed Asymmetric Addition of Optically Pure P-Chiral H-Phosphinates to Aldehydes Leading to Optically Active α-Hydroxyphosphinates. Chem. Eur. J. 2016, 22 (18), 6213-6217. (SCI-II, IF: 5.731) Highlighted by Synfacts: 
 (22) Xiaohui Li, Shuangyan Li, Qiang Li, Xu Dong, Yang Li, Xiaochun Yu, Qing Xu.* Efficient and Practical Catalyst-Free-Like Dehydrative N-Alkylation of Amines and Sulfinamides with Alcohols Initiated by Aerobic Oxidation of Alcohols under Air. Tetrahedron 2016, 72 (2), 264-272 (SCI-III, IF: 2.641). .   (23) Lei Yu,* Yaping Huang, Zheng Wei, Yuanhua Ding, Chenliang Su,* Qing Xu.* Heck Reactions Catalyzed by Ultrasmall and Uniform Pd Nanoparticles Supported on Polyaniline. J. Org. Chem.2015, 80 (17), 8677–8683 (SCI-II,IF: 4.721). 被X-MOL化学咨询平台亮点摘录:  (24) Lei Yu,* Jianqing Ye, Xu Zhang, Yuanhua Ding, Qing Xu.* Recyclable (PhSe)2-catalyzed selective oxidation of isatin by H2O2: a practical and waste-free access to isatoic anhydride under mild and neutral conditions. Catal. Sci. Technol. 2015, 5 (10), 4830-4838 (SCI-II, IF: 5.426). 
(25) Lei Yu,* Mingxuan Liu, Fenglin Chen and Qing Xu.* Heterocycles from Methylenecyclopropanes, Org. Biomol. Chem. 2015, 13, 8379-8392 (SCI-III, IF: 3.562, 外封面论文). .  (26) Xinkang Shi, Junmei Guo, Jianping Liu, Mingde Ye, Qing Xu.* Unexpectedly Simple Synthesis of Benzazoles by t-BuONa-Catalyzed Direct Aerobic Oxidative Cyclocondensation of o-Thio/Hydroxy/Aminoanilines with Alcohols under Air. Chem. Eur. J. 2015, 21 (28), 9988-9993 (SCI-II, IF: 5.731). Highlighted by Synfacts: Highlighted by as   (27) Shuangyan Li, Xiaohui Li, Qiang Li, Qiaochao Yuan, Xinkang Shi, Qing Xu.* Structure-Dependent Tautomerization Induced Catalyst-Free Autocatalyzed N-Alkylation of Heteroaryl Amines with Alcohols. Green Chem. 2015, 17 (6), 3260-3265 (SCI-II, IF: 8.02).  被X-MOL化学咨询平台亮点摘录:  (29) Xu Zhang, Jianqing Ye, Lei Yu,* Xinkang Shi, Ming Zhang, Qing Xu,* Mark Lautens. Organoselenium-Catalyzed Baeyer-Villiger Oxidation of α,β-Unsaturated Ketones by Hydrogen Peroxide to Access Vinyl Esters. Adv. Synth. Catal. 2015, 357 (5), 955-960 (SCI-II, IF: 5.663). 被Organic Chemistry Portal摘录:  (30) Qiang Li, Yao Huang, Tieqiao Chen, Yongbo Zhou,* Qing Xu, Shuang-Feng Yin,* Li-Biao Han. Copper-Catalyzed Aerobic Oxidative Amination of sp3C–H Bonds: Efficient Synthesis of 2-Hetarylquinazolin-4(3H)-ones. Org. Lett. 2014, 16 (14), 3672–3675 (SCI-II, IF: 6.364).  (31) Lei Yu,* Jun Wang, Hongen Cao, Kehong Ding, Qing Xu*, A Review on Catalyzed Dimerization of Acrylonitrile, Chin. J. Org. Chem. 2014, 37 (7), 1986-1991 (SCI, IF: 0.917).
 (32) Xiaojuan Jia, Lei Yu, Jianping Liu, Qing Xu,* Marcel Sickert, Lianhui Chen, and Mark Lautens.* Sulfur-silicon bond activation catalysed by Cl/Br ions: waste-free synthesis of unsymmetrical thioethers by replacing fluoride catalysis and fluorinated substrates in SNAr reactions, Green Chem. 2014, 16 (7), 3444-3449 (SCI-II, IF: 8.02).  (33) Lei Yu,* Jun Wang, Xu Zhang, Hongen Cao, Genling Wang, Kehong Ding, Qing Xu*, Mark Lautens. Practical preparation of 2-methyleneglutaronitrile via an efficient and highly selective head-to-tail dimerization of acrylonitrile catalyzed by low-loading tricyclohexylphosphine. RSC Adv. 2014, 4 (37), 19122-19126 (SCI-III, IF: 3.84).  (34) Haonan Chen, Wujie Dai, Yi Chen, Qing Xu,* Jianhui Chen, Lei Yu, Yajuan Zhao, Mingde Ye, Yuanjiang Pan.* Efficient and selective nitrile hydration reaction in water catalyzed by unexpected dimethylsulfinyl anion generated in situ from CsOH and DMSO. Green Chem. 2014, 16 (4), 2136-2141 (SCI-II, IF: 8.02).  (35) Lei Yu,* Hongyan Li, Xu Zhang, Jianqing Ye, Jianping Liu, Qing Xu,* Mark Lautens. Organoselenium-Catalyzed Mild Dehydration of Aldoximes: An Unexpected Practical Method for Organonitrile Synthesis. Org. Lett. 2014, 15 (3), 1346-1349 (SCI-II, IF: 6.364). 被Organic Chemistry Portal摘录:  (36) Qing Xu,* Jianhui Chen, Haiwen Tian, Xueqin Yuan, Shuangyan Li, Chongkuan Zhou, Jianping Liu. Catalyst-Free Dehydrative α-Alkylation of Ketones with Alcohols: Green and Selective Autocatalyzed Synthesis of Alcohols and Ketones. Angew. Chem. ; 浙江省基金网站报道: 
(37) Lei Yu,* Yulan Wu, Hongen Cao, Xu Zhang, Xinkang Shi, Jie Luan, Tian Chen, Yi Pan, Qing Xu.* Facile Synthesis of 2-Methylenecyclobutanones via Ca(OH)2-Catalyzed Direct Condensation of Cyclobutanone with Aldehydes and (PhSe)2-Catalyzed Baeyer-Villiger Oxidation to 4-Methylenebutanolides. Green Chem. 2014, 16 (1), 287-293 (SCI-II, IF: 8.02).  (38) Erlei Zhang, Haiwen Tian, Sendong Xu, XiaochunYu, Qing Xu.* Iron-Catalyzed Direct Synthesis of Imines from Amines or Alcohols and Amines via Aerobic Oxidative Reactions under Air. Org. Lett. 2013, 15 (11), 2704-2707 (SCI-II, IF: 6.364). 被Organic Chemistry Portal摘录:  (39) Quan Liu, Zhongxiang Lu, Wenfei Ren, Kaibo Shen, Yu Wang, Qing Xu.* Efficient Synthesis of Unsymmetrical Heteroaryl Ethers by a Transition Metal-Free C-O Cross-Coupling Reaction of Activated and Unactivated Heteroaryl Chlorides with Alcohols and Phenols. Chin. J Chem. 2013, 31 (6), 764-772 (SCI, IF: 0.917).  (40) Bo Huang, Haiwen Tian, Shoushuai Lin, Meihua Xie, Xiaochun Yu,* Qing Xu.* Cu(I)/TEMPO-Catalyzed Aerobic Oxidative Synthesis of Imines Directly from Primary and Secondary Amines under Ambient and Neat Conditions. Tetrahedron Lett. 2013, 54 (22), 2861-2864 (SCI-III, IF:  (41) Qing Xu,* Yong-Bo Zhou, Chang-Qiu Zhao, Shuang-Feng Yin, Li-Biao Han.* Transition Metal-Catalyzed Efficient and Green Transformations of P(O)−H Compounds to Functional Organophosphorus Compounds. Mini-Rev. Med. Chem. 2013, 13 (6), 824-835 (SCI-III, IF: 2.903). (42) Qing Xu,* Jianhui Chen, Quan Liu. Aldehyde-Catalyzed Transition Metal-Free Dehydrative β-Alkylation of Methyl Carbinols with Alcohols. Adv. Synth. Catal. 2013, 355 (4), 697-704 (SCI-II, IF: 5.663).  (43) Lei Yu,* Yulan Wu, Tian Chen, Yi Pan, Qing Xu.* Direct Synthesis of Methylene-1,2-dichalcogenolanes via Radical [3+2] Cycloaddition of Methylenecyclopropanes with Elemental Chalcogens. Org. Lett. 2013, 15 (1), 144-147 (SCI-II, IF: 6.364).  (44) Qing Xu,* Qiang Li, Xiaogang Zhu, Jianhui Chen. Green and Scalable Aldehyde-Catalyzed Transition Metal-Free Dehydrative N-Alkylation of Amides and Amines with Alcohols. Adv. Synth. Catal. 2013, 355 (1), 73-80 (SCI-II, IF: 5.663). 被Organic Chemistry Portal摘录:  (45) Qing Xu,* Qiang Li. Recent Advances of Transition Metal-Catalyzed Aerobic Dehydrative Reactions of Alcohols and Amines and Related Reactions. Chin. J. Org. Chem. 2013, 33 (1), 18-35 (SCI, IF: 0.741).  (46) Haiwen Tian, Xiaochun Yu, Qiang Li, Jianxin Wang, Qing Xu.* General, Green, and Scalable Synthesis of Imines from Alcohols and Amines by a Mild and Efficient Copper-Catalyzed Aerobic Oxidative Reaction in Open Air at Room Temperature. Adv. Synth. Catal. 2012, 354 (14-15), 2671-2677 (SCI-II, IF: 5.663). Cited and commented by as an exceptionally good method for imine preparation from alcohols and amines)   (47) Qing Xu, Chang-Qiu Zhao, Yong-Bo Zhou, Shuang-Feng Yin, Li-Biao Han.* Transition Metal-Catalyzed Transformations of P(O)-H Bonds. Chin. J. Org. Chem. 2012, 32 (10), 1761-1775 (SCI, IF: 0.741; 外封面论文).  (48) Xiaochun Yu, Lan Jiang, Qiang Li, Yuanyuan Xie, Qing Xu.* Palladium-Catalyzed N-Alkylation of Amides and Amines with Alcohols Employing the Aerobic Relay Race Methodology. Chin. J. Chem. 2012, 30 (10), 2322-2332 (SCI, IF: 0.917).  Highlighted by Org. Biomol. Chem. as Outside Front Cover Paper. Featured in the top 10% of the most highly cited articles published in the latest Impact Factor window 2011-2012)  (50) Shiheng Liao, Kangkang Yu, Qiang Li, Haiwen Tian, Zhengping Zhang, Xiaochun Yu, Qing Xu.* Copper-Catalyzed C-Alkylation of Secondary Alcohols and Methyl Ketones with Alcohols Employing the Aerobic Relay Race Methodology. Org. Biomol. Chem. Highlighted by Org. Biomol. Chem. as Front Cover Paper. Featured in the top 10% of the most highly cited articles published in the latest Impact Factor window 2011-2012)  (51) Xiaochun Yu, Chuanzhi Liu, Lan Jiang, Qing Xu.* Manganese Dioxide Catalyzed N-Alkylation of Sulfonamides and Amines with Alcohols under Air. Org. Lett. 2011, 13 (23), 6184-6187 被Organic Chemistry Portal摘录:  (52) Lan Jiang, Luolu Jin, Haiwen Tian, Xueqin Yuan, Xiaochun Yu,* Qing Xu.* Direct and Mild Palladium-Catalyzed Aerobic Oxidative Synthesis of Imines from Alcohols and Amines under Ambient Conditions. Chem. Commun. 2011, 47 (38), 10833-10835 (SCI-II, IF: 6.834). 、  (53) Chuanzhi Liu, Shiheng Liao, Qiang Li, Sunlin Feng, Qing Sun, Xiaochun Yu,* Qing Xu.* Discovery and Mechanistic Studies of a General Air-Promoted Metal-Catalyzed Aerobic N-Alkylation Reaction of Amides and Amines with Alcohols. J. Org. Chem. 2011, 76 (14), 5759-5773 (SCI-II,  (54) Sun Lin Feng, Chuan Zhi Liu, Qiang Li; Xiao Chun Yu, Qing Xu.* Rhodium-Catalyzed Aerobic N-Alkylation of Sulfonamides with Benzylic Alcohols. Chin. Chem. Lett. 2011, 22 (9), 1021-1024. (SCI, IF: 1.21) 、《中国化学快报》2013年度高被引论文 (55) Chuanzhi Liu, Xufeng Zang, Baohua Yu, Xiaochun Yu,* Qing Xu.* Microwave-Promoted TBAF-Catalyzed SNAr Reaction of Aryl Fluorides and ArSTMS: an Efficient Synthesis of Unsymmetrical Diaryl Thioethers. Synlett, 2011, (8), 1143-1148 (SCI-III, IF: 2.655).  (56) Qing Xu, Ruwei Shen, Yutaka Ono, Ritsuko Nagahata, Shigeru Shimada, Midori Goto, Li-Biao Han.* A New Oxapalladacycle Generated via Ortho C-H Activation of Phenylphosphinic Acid: Efficient Catalyst for Markovnikov-Type Additions of E-H Bonds to Alkynes. Chem. Commun. 2011, 47 (8), 2333-2335 (SCI-II, IF: 6.834). 被Organic Chemistry Portal摘录: 被Labome摘录:  (57) Qing Xu, Han, Li-Biao.* Metal-catalyzed additions of H-P(O) bonds to carbon-carbon unsaturated bonds. J. Organometallic Chem. 2011, 696 (1), 130-140 (SCI, IF: 2.0).  (58) Qing Xu,* Li-Biao Han.* Transition Metal-Catalyzed Selective Hydrophosphorylation Reactions. (59) Qing Xu, Chang-Qiu Zhao, Li-Biao Han.* Stereospecific Nucleophilic Substitution of Optically Pure H-Phosphinates: A General Way for the Preparation of Chiral P-Stereogenic Phosphine Oxides. J. Am. Chem. Soc. 2008, 130 (38), 12648-12655 (SCI-I, IF: 12.113). 该工作被日本《化学工业日报》和研究同行高度评价    本人参与Han教授的该系列工作2015年4月和9月分别获得日本科学技术奖(日本文部科学大臣表彰)和筑波奖励奖(つくば奨励賞)  (60) Qing Xu, Li-Biao Han.* Palladium-Catalyzed Asymmetric Hydrophosphorylation of Norbornenes. Org. Lett. 2006, 8 (10), 2099-2101 (SCI-II, IF: 6.364).  (61) Qing Xu, Xian Huang,* Jingqi Yuan. Facile Synthesis of β-Organotellurobutenolides via Electrophilic Tellurolactonization of α-Allenoic Acids. J. Org. Chem. 2005, 70 (17), 6948-6951  (62) Qing Xu, Xian Huang.* Cis-Carbocuperation of Acetylenic Sulfoxides and Corresponding Applications in the Regio- and Stereoselective Synthesis of Polysubstituted Vinyl Sulfoxides. Tetrahedron Lett. 2004, 45 (29), 5657-5660. (SCI-III, IF: 2.379)  (63) Qing Xu, Xian Huang,* Jun Ni. Hydrotelluration and Carbotelluration of Acetylenic Sulfoxides: Regio- and Stereoselective Preparation of α- and β-Organotellurovinyl Sulfoxides. Tetrahedron Lett. 2004, 45(14), 2981-2984 (SCI-III, IF: 2.379).  |