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张名镇 博士
研究员,博士生导师
应用化学系
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    • 高分子纳米胶束或有机-无机复合纳米颗粒用于构建靶向肿瘤的纳米诊疗体系、生物传感器以及高分子自组装

个人简介


个人简介

张名镇,研究员,博士生/硕士生导师。北京化工大学高分子系,学士和硕士;加拿大滑铁卢大学(University of Waterloo)化学系,化学哲学博士。2005-2006,加拿大蒙特利尔大学(University of Montreal)药学院博士后;2006-2008,日本东京大学(University of Tokyo)材料系日本学术振兴会(JSPS)特别研究员。2008年底回国工作,先后担任温州医科大学、杭州电子科技大学研究员、博士生导师。其间,赴美国休斯顿卫理公会医院研究所(Houston Methodist Research Institute)纳米医学系和北卡大学教堂山分校(University of North Carolina at Chapel Hill)药学院开展研究。202112月加入温州大学从事教学和科研工作。

 

已主持国家自然科学基金2项、省部级课题2项;作为核心成员,参与浙江省科技计划重大项目和浙江省高校创新团队各1项。曾入选浙江省钱江人才计划。作为第一作者或通讯作者,已在纳米医学、生物材料或高分子科学领域的国际知名期刊,如Advanced MaterialsNano TodayBiomaterialsJournal of Controlled ReleaseMacromolecules等,发表论文近20篇,获授权美国专利1项。

 

担任SCI期刊(如ACS NanoAdvanced Functional MaterialsBiomaterialsJournal of Controlled ReleasePolymer等)的审稿人。受邀担任浙江省自然科学杰出青年及浙江省科技计划重大专项会议评审专家、教育部学位论文评审专家、广东省自然科学基金函评专家、杭州市和温州市科技计划重点项目会议评审专家。

 

代表性著作

1. Zhang, M.Z*., Chen, X., Li, C., Shen, X. Charge-reversal nanocarriers: An emerging paradigm for smart cancer nanomedicine. Journal of Controlled Release 2020, 319, 46-62.

2. Dai, D.X., Liu, H.Y., Gu, C.C., Zhang, M.Z.* Facile synthesis of Cu2O-Au nanocomposites as nanozyme for colorimetric determination of hydrogen peroxide. Journal of Alloys and Compounds 2018, 747, 676-683.

3. Liu, H.Y., Jiao, M.R., Gu, C.C., Zhang, M.Z.* Au@CuxOS yolk-shell nanomaterials with porous shells act as a new peroxidase mimics for colorimetric detection of H2O2. Journal of Alloys and Compounds 2018, 741, 197-204.

4. Hou, C., Liu, H.Y., Zhang, D., Yang, C., Zhang, M.Z.* Synthesis of ZnO nanorods-Au nanoparticles hybrids via in-situ plasma sputtering-assisted method for simultaneous electrochemical sensing of ascorbic acid and uric acid. Journal of Alloys and Compounds 2016, 666, 178-184.

5. Liu, H.Y., Gu, C.C., Xiong, W.W., Zhang, M.Z.* A Sensitive Hydrogen Peroxide Biosensor Using Ultra-small CuInS2 Nanocrystals As Peroxidase Mimics. Sensors and Actuators B-Chemical 2015, 209, 670-676.

6. Zhang, M.Z., Xu, R., Yang, Y., Xia, X., Qin, G.T., Ferrari, M., Shen, H. Polycation-Functionalized Nanoporous Silicon Particles for Gene Silencing on Breast Cancer Cells. Biomaterials 2014, 35, 423-431.

7. Pittella, F., Zhang, M.Z., Lee, Y., Kim, H.J., Miyata, K., Nishiyama, N., Kataoka, K. Enhanced Endosomal Escape of siRNA-Incorporating Hybrid Nanoparticles from Calcium Phosphate and PEG-Block Charge Conversional Polymer for Efficient Gene Knockdown with Negligible Cytotoxicity. Biomaterials 2011, 32, 3106-3114.

8. Zhang, M.Z., Kataoka, K. Nano-Structured Composites Based on Calcium Phosphate for Cellular Delivery of Therapeutic and Diagnostic Agents. Nano Today 2009, 4, 510-517.

9. Zhang, M.Z., Ishii, A., Nishiyama, N., Matsumoto, S., Yamasaki, Y., Kataoka, K. PEGylated Calcium Phosphate Nanocomposites as Smart Environmental-Sensitive Carriers for siRNA Delivery. Advanced Materials 2009, 21, 3520-3525.

10. Zhang, M.Z., Duhamel, J. Study of Microcrystallization of Ethylene-Propylene Copolymers in Solution by Fluorescence. Macromolecules 2007, 40, 661-669.