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祝贺张兴国老师指导研究生在The Journal of Organic Chemistry上发表学术论文

添加时间:2017年12月14日 浏览:

标题:One-Pot Synthesis of Quinoxalinones via Tandem Nitrosation/Cyclization of NAryl Cyanoacetamides

AbstactA new one-pot strategy for the synthesis of quinoxalin-2-ones from the tandem nitrosation/cyclization reaction of N-aryl cyanoacetamides with tert-butyl nitrite has been developed. The dehydrogenative N-incorporation is achieved through a sequence of nitrosation, tautomerization, and cyclization, affording quinoxalin-2-ones in moderate to good yields with good functional group tolerance.


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